Synthetrial

synthetrial.com ↗ ·Alcalá de Henares ·Pre-seed

Synthetrial is a Spanish deeptech startup that uses generative AI to create synthetic patient data from small samples of real, anonymised patient data, helping pharma, cosmetics and medtech sponsors design, simulate and analyse clinical trials faster and at lower cost. Its models generate 'synthetic patients' that preserve statistically relevant distributions, letting trials reach significance with fewer recruits, predict trial evolution and discard weak research lines earlier. Incorporated as Synthetrial SL in Alcalá de Henares (Madrid) in June 2024, it holds ENISA emerging-company certification and has gone through the healthstart madri+d, RETECH Madrid and Kunsen digital-health acceleration programmes, winning Madrid Impacta 2025 'Social Enterprise of the Year'.

Founded

2024

Founders

Total funds raised

—

Rounds

SectorsHealthtech & Bio, AI & Data, Clinical trials, Synthetic data, Pharma Start-up MapHealthtech & Bio › Clinical software & health data

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Founders

José Ignacio Klett Mingo

CEO & Co-founder

Julio Cambronero Plaza

Co-founder

Global models 5

Owkin

France · www.owkin.com ↗

Sells AI models built on patient data to pharma sponsors to design and optimise clinical trials, including synthetic and external control arms.

~$300MComparable

Unlearn

United States · www.unlearn.ai ↗

Uses generative AI to build digital-twin synthetic patients, so pharma sponsors can run smaller and faster trials that still reach statistical power, which is the same model as Synthetrial's.

~$135MComparable

Aitia

United States · aitiabio.com ↗

Builds causal AI 'digital twins' of patients from real-world and trial data, and sells simulation of trial outcomes and drug responses to pharma.

~$60MComparable

QuantHealth

Israel · www.quanthealth.ai ↗

Sells AI-based clinical trial simulation to pharma sponsors, predicting trial results in advance so they can drop weak designs and trial candidates early.

~$20MComparable

Syntegra

United States · www.syntegra.io ↗

Used generative AI to create privacy-preserving synthetic patient data from real healthcare records, sold to pharma and life-sciences companies for research and trial analysis.

~$5MComparable