Pragmatech

pragmatech.ai ↗ ·Oviedo ·Pre-seed

Pragmatech is an Oviedo-based healthtech company that develops artificial intelligence for clinical microbiology and infectious diseases. Its main product, iAST, is clinical decision-support software that predicts which antibiotic is likely to work for a patient before laboratory results are available, helping hospitals prescribe antibiotics more efficiently and safely. iAST received CE marking in July 2025, and the company also offers data engineering, NLP, predictive modelling and diagnostic-algorithm services to the healthcare sector. Founded in 2021 by Pablo Valledor and Javier Fernández, the company closed a €650k seed round in December 2025 led by First Drop with Urriellu Ventures, which included a €180k ENISA loan and the conversion of earlier convertible notes.

Founded

2021

Founders

Total funds raised

€638K

SectorsHealthtech, Artificial Intelligence, Clinical Decision Support, Infectious Diseases Start-up MapHealthtech & Bio › Clinical software & health data

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Founders

Javier Fernández Domínguez

Founder, Co-CEO & CSO

Pablo Valledor

Founder, Co-CEO & CTO

Global models 5

Dascena

United States · www.dascena.com ↗

Like iAST, it sells hospitals machine-learning decision-support software that runs on clinical data and flags infections such as sepsis before lab confirmation; the figure is its $50M Series B only, because its earlier Series A amount was never disclosed.

$50MComparable

Day Zero Diagnostics

United States · www.dayzerodiagnostics.com ↗

Its Keynome machine-learning engine predicts a pathogen's antibiotic susceptibility hours before culture-based testing, the same goal as iAST, although it pairs the AI with its own sequencing sample-preparation workflow sold to hospital labs.

$49MComparable

Prenosis

United States · prenosis.com ↗

It sells hospitals Sepsis ImmunoScore, a regulator-cleared AI diagnostic that combines clinical data and biomarkers to guide care for infections; the figure is the 2026 Series A equity only, because the announced $40M adds a $20M BARDA contract and earlier totals mix equity with grants.

$20MComparable

Bayesian Health

United States · www.bayesianhealth.com ↗

A Johns Hopkins spin-out that licenses its FDA-cleared AI clinical decision-support platform (TREWS) to health systems for early sepsis and infection detection, a software-to-hospital model like Pragmatech's.

$15MComparable

Mednition

United States · mednition.com ↗

It sells hospitals KATE, a machine-learning decision-support tool with an FDA Breakthrough-designated sepsis module; it is a looser match because its core use is emergency-department triage.

$10MComparable

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Notes: Most funded first

Investors 3

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First Drop VC

www.firstdropvc.com

Led Pre-seed 2025 Spain

Urriellu Ventures

urriellu.com

Pre-seed 2025 Spain

Santiago Romero Brufau

Pre-seed 2023 United States

Funding rounds 2

·1 not counted

Date	Round	Amount	Lead
2025-12-30	Pre-seed (estimated)	€475K	First Drop VC +1 more
2023-04	Pre-seed	€163K	Lead not disclosed +1 more

Not counted (1)

Not counted in totals

2025-12-30 Public Loan €180K ENISA

News 4

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Published	Article
2025-12-31	Spanish HealthTech Pragmatech raises €650k to roll out its CE-marked AI antibiotic prescribing software ↗ EU-Startups +2 sources 3 reportsfirst 2025-12-31 Spanish HealthTech Pragmatech raises €650k to roll out its CE-marked AI antibiotic prescribing softwareEU-Startups · 2025-12-31↗ Spainish firm Pragmatech closes €650k funding to boost AI antibiotic prescribing softwareVestbee · 2026-01-02↗ Spanish AI Startup Pragmatech Secures €650k Funding to Transform Antibiotic PrescribingEntrepreneur Loop · 2026-01-03↗ 2025-12-31
2025-12-30	Pragmatech closes a €650,000 funding round led by First Drop ↗ Capital-Riesgo.es 2025-12-30
2025-07-11	Un software español que utiliza la IA para la prescripción de medicamentos obtiene el marcado CE ↗ IM Médico Hospitalario 2025-07-11
2023-04-21	AV Law advises Pragmatech AI Solutions on its first financing round ↗ AV Law 2023-04-21