OOna Therapeutics
Ona Therapeutics is a Barcelona-based clinical-stage biotech developing first-in-class antibody-drug conjugates (ADCs) and antibodies against advanced and treatment-resistant solid tumours, built on research into metastasis-initiating cells and lipid metabolism. Spun out of IRB Barcelona and ICREA in 2019, it runs three internal ADC programmes (ONA-255 for breast cancer and solid tumours, ONA-389, and dual-payload ONA-418). It raised a €30M Series A in 2020 and an oversubscribed €74.2M (~$86.6M) Series B in June 2026, one of the largest life-sciences rounds in Catalonia.
SectorsBiotech, Oncology, Antibody-Drug Conjugates, Pharmaceuticals, Life Sciences
Start-up MapHealthtech & Bio › Drug discovery & therapeutics developers
Founders
S
Salvador Aznar Benitah
Scientific Co-founder (ICREA Research Professor, IRB Barcelona)
V
Valerie Vanhooren
Co-founder & Chief Executive Officer
Global models 5
TTubulis
Germany · tubulis.com ↗
Venture-backed clinical-stage biotech developing its own antibody-drug conjugates (ADCs) against solid tumours, on the path to licensing or selling its programmes to large pharma.
~$580MComparable
AAvenzo Therapeutics
United States · www.avenzotx.com ↗
Venture-backed oncology biotech advancing its own ADC and targeted-therapy programmes for solid tumours through clinical trials.
~$236MComparable
CCallio Therapeutics
United States · www.calliotx.com ↗
Develops its own dual-payload ADCs for treatment-resistant solid tumours, the same approach as Ona's ONA-418.
~$187MComparable
AAdcendo
Denmark · www.adcendo.com ↗
European venture-backed biotech developing first-in-class ADCs against new solid-tumour targets, taking its own programmes into the clinic.
~$140MComparable
PPheon Therapeutics
United Kingdom · www.pheontx.com ↗
European venture-backed biotech developing next-generation ADCs for hard-to-treat solid tumours, aiming to license or sell its programmes to pharma.
~$120MComparable
In the same niche 67 others
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Notes: Most funded first
Investors 11
Open as list →
AAsabys Partners
www.asabys.com
CCentro para el Desarrollo Tecnológico y la Innovación
cdti.es
CColumbus Venture Partners
columbusvp.com
AAlta Life Sciences
www.altalifesciences.com
YYsios Capital
www.ysioscapital.com
CCOFIDES
www.cofides.es
MMérieux Equity Partners
B
Bpifrance
F
Fund+
FFundPlus
KKorys
Funding rounds 4
| Date | Round | Amount | Lead |
|---|---|---|---|
| 2026-06-04 | Series B | €74.2M |
Columbus Venture Partners, Mérieux Equity Partners
+9 more
|
| 2025-10-08 | Series A | €10M |
CDTI Innovación (SICC Innvierte)
+4 more
|
| 2020-06-17 | Series A | €30M |
Lead not disclosed
+5 more
|
| 2019-05-20 | Seed | €1.5M | Asabys Partners |
News 4
Open as list →| Published | Article |
|---|---|
| 2026-10-26 |
Las startups en España rozan los 4.000 millones de euros invertidos, en 2026 ↗
MuyPymes
2026-10-26 |
| 2026-09-10 |
Spain's top-funded tech companies in H1 2026 ↗
Tech.eu
2026-09-10 |
| 2026-06-04 |
Ona Therapeutics bags $86.6m to push cancer-fighting ADCs into human trials ↗
BioXconomy
2026-06-04 |
| 2026-06-04 |
Ona Therapeutics Raises $86.6 Million Series B to Advance First-in-Class ADCs into Clinical Development ↗
GlobeNewswire
2026-06-04 |