Highlight Therapeutics

www.highlighttherapeutics.com ↗ ·Valencia ·Series B

Highlight Therapeutics (formerly Bioncotech Therapeutics) is a private, clinical-stage biopharmaceutical company developing intralesional RNA-based immunotherapies for dermato-oncology. Its lead candidate BO-112, derived from CNIO melanoma research, turns immunologically 'cold' tumours 'hot' and is in a Phase 2b trial (SPOTLIGHT-204) in basal cell carcinoma, plus combination studies with anti-PD1 in melanoma. It is headquartered in the Valencia Science Park (Paterna, Valencia), and in September 2025 it raised €15M in a round led by Buenavista.

Founded
2010
Founders
2
Total funds raised
€46.6M
Rounds
3
Investors
5
Last round
Sep 2025
SectorsBiotech, Immuno-oncology, Pharmaceuticals, RNA therapeutics, Dermato-oncology Start-up MapHealthtech & Bio › Drug discovery & therapeutics developers

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Founders

Damià Tormo
Co-founder and Board Member (founding CEO of Bioncotech Therapeutics)
María S. Soengas
Scientific Co-founder (Head of Melanoma Group, CNIO)

Global models 3

Oncorus
United States
Clinical-stage biotech that raised VC to develop intratumorally injected immunotherapies meant to turn cold tumours hot, the same asset-driven model as Highlight.
$137MComparable
Checkmate Pharmaceuticals
United States
VC-backed clinical-stage company that developed an intratumoral nucleic-acid innate-immune agonist (TLR9, CMP-001) combined with anti-PD-1 in melanoma, mirroring BO-112's approach.
$125MComparable
Replimune
United States · www.replimune.com ↗
Raised venture capital before its IPO to develop intralesional immunotherapy (RP1) for skin cancers, including combinations with anti-PD-1 in melanoma, which is Highlight's dermato-oncology strategy.
$110MComparable

In the same niche 67 others

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Notes: Most funded first

Investors 5

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Funding rounds 3

DateRoundAmountLead
PublishedArticle
2025-09-16 Buenavista leads a €15 million funding round in Highlight Therapeutics ↗
Capital-Riesgo.es
2025-09-16
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