Minoryx Therapeutics

minoryx.com ↗ ·Mataró ·Series C

Minoryx Therapeutics is a clinical/registration-stage biotech company based in Mataró (Barcelona) developing novel therapies for orphan central nervous system diseases with high unmet medical need, prioritising paediatric genetic neurometabolic conditions. Its lead asset, leriglitazone (NEZGLYAL, MIN-102), is a brain-penetrant selective PPAR-gamma agonist for X-linked adrenoleukodystrophy that received a positive CHMP opinion in July 2026 for cerebral ALD, with European Commission marketing authorisation expected by end of September 2026; a Phase 2 trial in Rett syndrome (TREE) is due to read out by end of 2026. The company was founded in 2011, spun off its SEE-Tx platform into Gain Therapeutics in 2018, raised a €51M Series C in 2022, and secured a €26.9M IPCEI Med4Cure grant in 2025.

Founded
2011
Founders
3
Total funds raised
€95.6M
Rounds
5
Investors
16
Last round
May 2022
SectorsBiotech, Pharmaceuticals, Rare Diseases, CNS / Neurology, Drug Discovery Start-up MapHealthtech & Bio › Drug discovery & therapeutics developers

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Founders

Joan Aymamí
Co-founder
Marc Martinell
Co-founder & CEO
Xavier Barril
Co-founder

Global models 5

Encoded Therapeutics
United States · encoded.com ↗
Private clinical-stage biotech developing therapies for severe paediatric genetic CNS disorders, which it plans to license or take to market for orphan indications.
~$240MComparable
Passage Bio
United States · www.passagebio.com ↗
VC-built clinical biotech targeting rare monogenic paediatric CNS diseases, including leukodystrophies, for approval under orphan-drug rules.
~$225M (pre-IPO)Comparable
Praxis Precision Medicines
United States · praxismedicines.com ↗
VC-backed biotech developing CNS drugs for rare genetic paediatric epilepsies and taking them through registration trials.
~$210M (pre-IPO)Comparable
Neurogene
United States · www.neurogene.com ↗
Clinical-stage company developing therapies for rare paediatric neurological genetic diseases, with Rett syndrome as its lead indication, the same indication as Minoryx's TREE trial.
~$200M (pre-IPO)Comparable
Autobahn Therapeutics
United States · www.autobahntx.com ↗
VC-funded developer of brain-penetrant small molecules for CNS disorders; its lead programme targets adrenoleukodystrophy, the same disease as leriglitazone.
~$176MComparable

In the same niche 67 others

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Notes: Most funded first

Investors 16

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Funding rounds 5

DateRoundAmountLead

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