OneChain Immunotherapeutics

onechaintx.com ↗ ·Barcelona ·Pre-Series A

OneChain Immunotherapeutics is a clinical-stage biotech company in Barcelona developing CAR-T cell therapies for haematological cancers, spun out in June 2020 from the Josep Carreras Leukaemia Research Institute and ICREA based on research led by Dr. Pablo Menéndez. Its lead asset OC-1 targets CD1a in cortical T-cell acute lymphoblastic leukaemia (first patient dosed in the CARxALL trial at Hospital Clínic and Hospital Sant Joan de Déu; FDA Orphan Drug designation), alongside a CD22 programme and in vivo CAR-T work via a collaboration with NanoCell Therapeutics. It raised a €6.7M pre-Series A in 2023 led by Invivo Capital and is part of a consortium awarded a €3.8M grant for AI-designed targeted viral particles.

Founded
2020
Founders
2
Total funds raised
€9.8M
Rounds
2
Investors
7
Last round
Jun 2023
SectorsBiotech, Immuno-oncology, CAR-T cell therapy, Healthtech & Bio, Deeptech Start-up MapHealthtech & Bio › Drug discovery & therapeutics developers

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Founders

Jorge Alemany
Co-founder and former CEO (2020–2024)
Pablo Menéndez
Founder, President and Chief Scientific Officer

Global models 5

Allogene Therapeutics
United States · www.allogene.com ↗
Clinical-stage biotech developing CAR-T cell therapies for blood cancers, funded by venture capital before its IPO, like OneChain.
$400MComparable
Umoja Biopharma
Venture-backed biotech developing in vivo CAR-T therapies for cancer, the same approach as OneChain's in vivo CAR-T programme.
$360MComparable
Juno Therapeutics
United States
Academic spin-out that raised large venture rounds to take CD19 CAR-T therapies for leukaemia and lymphoma into the clinic, the path OneChain is following.
$310MComparable
Cargo Therapeutics
United States · www.cargo-tx.com ↗
Clinical-stage, VC-funded CAR-T company targeting haematological cancers (CD22 CAR-T in lymphoma), which overlaps with OneChain's CD22 programme.
$300MComparable
Arcellx
United States · www.arcellx.com ↗
Venture-backed, clinical-stage cell therapy biotech developing CAR-T treatments for haematological cancers such as multiple myeloma and leukaemia.
$200MComparable

In the same niche 67 others

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Notes: Most funded first

Investors 7

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Funding rounds 2

DateRoundAmountLead

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