Thytech

inmunoregulacion.es ↗ ·Madrid ·Pre-seed

Thytech is a Madrid-based biotech spin-off of the Gregorio Marañón Health Research Institute (IISGM) developing cell therapies based on regulatory T cells obtained from thymic tissue (thyTregs), a novel cell source pioneered by its founders' Immunoregulation Laboratory. Its lead programme targets prevention of graft rejection in pediatric heart transplantation — it performed the world's first-in-human thyTreg therapy in a transplanted infant (published in the Journal of Experimental Medicine) — with further applications in autoimmune and inflammatory diseases. Founded in 2022, it raised a ~€350K seed round led by Banco Sabadell's BStartup Health, later added Farmalider as industrial partner via a capital increase (June 2026), and has secured over €2M in public funding from Spain's State Research Agency and CDTI.

Founded
2022
Founders
4
Total funds raised
€350K+
Rounds
2
Investors
3
Last round
Jun 2026
SectorsBiotech, Cell Therapy, Immunology, Healthtech & Bio Start-up MapHealthtech & Bio › Drug discovery & therapeutics developers

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Founders

Esther Bernaldo de Quirós Plaza
Co-founder & Head of Process Development and Quality Control
Marjorie Pion
Co-founder & Head of Genetic Engineering Program for Cell Therapy
Marta Martínez Bonet
Co-founder & Head of Characterization and Manufacturing Sciences
Rafael Correa-Rocha
Co-founder & Chief Scientific Officer

Global models 5

Orca Bio
United States · orcabio.com ↗
Develops high-precision cell therapies built on regulatory T cells to prevent immune complications around transplantation.
$440MComparable
Sonoma Biotherapeutics
United States · sonomabio.com ↗
Develops engineered regulatory T-cell therapies for autoimmune and inflammatory diseases.
$335MComparable
Quell Therapeutics
United Kingdom · quell-tx.com ↗
Academic spin-off developing engineered Treg cell therapies, led by a programme to induce tolerance after organ (liver) transplantation.
$206MComparable
GentiBio
United States · gentibio.com ↗
Develops engineered regulatory T-cell therapies for autoimmune, alloimmune and inflammatory diseases.
$177MComparable
Abata Therapeutics
United States · abatatx.com ↗
Develops regulatory T-cell therapies for autoimmune and inflammatory diseases.
$95MComparable

In the same niche 67 others

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Notes: Most funded first

Investors 3

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Funding rounds 2

DateRoundAmountLead

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